ROLE OF NITRIC OXIDE ISOFORMS IN VASCULAR AND ALVEOLAR DEVELOPMENT AND LUNG INJURY IN VASCULAR ENDOTHELIAL GROWTH FACTOR OVEREXPRESSING NEONATAL MICE LUNGS.

Role of Nitric Oxide Isoforms in Vascular and Alveolar Development and Lung Injury in Vascular Endothelial Growth Factor Overexpressing Neonatal Mice Lungs.

The role of vascular endothelial growth factor (VEGF)-induced 3 different nitric oxide synthase (NOS) isoforms in lung development and injury in the newborn (NB) lung are not known.We hypothesized that VEGF-induced specific NOS pathways are critical regulators of lung development and injury.We studied NB wild type (WT), lung epithelial cell-targete

read more



Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi.

One virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing.Serum-resistant B.burgdorferi express up to five distinct complement regulator-acquiring surface proteins (CRASP) which interact with complement regulator factor H (CFH) and charger factor H-like protein 1 (FHL1) or fact

read more

Molecular analysis of an integrative conjugative element, ICEH, present in the chromosome of different strains of Mycoplasma hyopneumoniae

Diversification of bacterial species and pathotypes is largely caused by lateral gene transfer (LGT) of diverse mobile DNA elements such as plasmids, phages, transposons and genomic islands.Thus, acquisition of new phenotypes by LGT is very important for bacterial evolution and relationship with hosts.This paper reports a 23 kb region containing fo

read more